Financial Highlights

¹ This is a Non GAAP financial measure. The most directly comparable measure under U.S. GAAP is Operating Income from continuing operations (FY 2017: $2,455m).

² This is a non GAAP financial measure. Non GAAP EBITDA margin calculated using Non GAAP EBITDA as a percentage of Non GAAP Total revenues. The most directly comparable measure under U.S. GAAP is Net income margin (FY 2017: 28%).

³ This is a Non GAAP financial measure. The most directly comparable measure under U.S. GAAP is Net cash provided by operating activities (FY 2017: $4,257m).

⁴ Diluted weighted average number of ordinary shares of 912 million.

⁵ This is a Non GAAP financial measure. The most directly comparable measure under U.S. GAAP is Diluted earnings per ADS.

⁶ This is a Non GAAP financial measure. Refer to Non GAAP financial measures on pages 179 to 183 of our 2017 Annual Report.

For Takeda's financial highlight, please refer to https://www.takeda.com/investors/financial-data/